Restoring the Gut: Understanding the 5 Rs to Healing Leaky Gut (2024)

hi everyone hi well

i want to welcome you to this week’s group visit

um we’re going to be continuing the conversation i started

i guess about the last months or so ago

about about intestinal permeability it’s a really important topic in

functional medicine and it’s important that we really lay this as a foundation to everything

we do and i really want you all to kind of understand

why we go about the things we do and or the importance or just kind of how we go about this so

i am mary scout i’m a physician assistant here i may even be your physician assistant

here so just to to bring up a few housekeeping

reminders if the the zoom kind of goes out uh give us maybe about 10 minutes

may take less time but to get back up and running we’ll be going as soon as we can also if you have any questions put

them in the chat box i will address them at the end of

this discussion so so restoring the gut understanding the five r’s to healing

leaky gut

i want to to recap discussed last time and

leaky gut and why that matters so it’s important to know that all

disease begins in the gut um this hippocrates is the kind of founder

of modern medicine and i don’t know why conventional medicine doesn’t follow this

so kind of this is a good depiction of what leaky gut is another more proper term is going to be intestinal

permeability so normally what

we want to see is we want to see these epithelial testosterone cells really

close and tight together these cells are going to be very selective as far as

what they’re going to allow through either nutrients

that kind of cross that prosthetic gut after you kind of break down the food that you consume or liquids they can go

kind of between these cells this is going to be highly selective or if kind of right they can go through

those cells and then they can get to the bloodstream and the bloodstream can help get these

nutrients to the organs and tissues that it needs to to promote and produce health and keep

you going well what happens in leaky gut whether it’s due to

stress alcohol antibiotic use

non-steroidal anti-inflammatory medications proton pump inhibitors like acid

reducers good allergens infections toxins

etc we can get leaky gut and you’ll see where those

junctions between those epithelial cells then widen

or things that are pathogens or food particles are now able

aside from foods they’re now able to get through the cells

between them or through them then we get things into our bloodstream that we don’t want and so on the other side here

starts our immune system reaction and so that can start to create inflammation

that inflammation can get it kind of go systemically i can go to our brains

and then we’ve really got a problem so kind of the problem at hand

and why we want to solve this is that this is going to be linked to so many of our health conditions and

concerns so things like autoimmune diseases being

cautious rheumatoid arthritis psoriasis and many many more some sort of bowel

disease um osteoarthritis hives eczema

other rashes i think martial psoriasis think acne environmental allergies food allergies

of course um acne mood disorders anxiety depression even links to schizophrenia

chronic fatigue issues autism dementia obesity if you’re having trouble losing

weight your gut maybe the issue and then of course

some things that are more obvious things like ibs or irritable bowel syndrome

um this picture kind of cracks me up because i whenever i try to explain leaky gut to

my patients i like to say it’s not that you have these fluids spewing out of your intestines into your body cavity

and so on and so forth but um so this is your not actual leaky gut depiction

so that’s kind of my really brief recap

what i like to think about gut healing and i want to know i want

you to think about what you have heard before maybe coming to maxwell clinic or

from the media or bloggers etc about what you know about guy healing

so before i came to maxwell i think gut healing was like drink kombucha they’ve

got good bacteria in that vinegary fermented substance it’s really good for your health

so i started drinking kombucha little did i know some of those coffee just had a lot more sugar which is actually not

good for your gut health i thought this was kefir or kefir kefir

is a fermented kind of dairy beverage again probiotics are the theme here

probiotics in general so there are so many probiotics on the market

but i’d like to i would encourage you to use these judiciously meaning

there’s a probiotic may not be right for everyone and higher doses of probiotics especially may not be right for a

particular individual you’re probably going to be safe with a lower dose probiotic think something about 30

billion cfus but otherwise you may run into some problems especially if you have

something called small intestinal bowel overgrowth and actually make your symptoms of like abdominal pain bloating

worse so just because they say probiotics are good doesn’t mean they’re right for you

being gluten-free i think in the last maybe five ten years we have seen this explosion of

gluten-free products and items it’s become almost more like a marketing term and then people have begun to assess or

to identify gluten-free as healthy well everything gluten-free is not necessarily healthy a lot of gluten-free

items are still heavily processed foods and could still cause inflammation in the bodies

and then bone broth bone broth is actually really beneficial to our gut health but that was something

i remember and trying to get on board with as well

so what actually is gut healing

it’s the 5r framework so i want to start to dig into that

now so the 5r framework is is very

foundational for functional medicine practitioners and it’s something that we

are all taught as we become certified in this type of medicine

so because a functioning digestive system is so essential to

good health and you’re you’re gonna these these issues

can cause more than just kind of your gastrointestinal complaints you might not just have floating gas

diarrhea like i said earlier it’s going to underlie your chronic health conditions um

that i mentioned earlier so there’s so much that can go wrong in our

gut and so if you think about our gut um our gut is a tube running from our

mouth to our anus and it is where our out the outside environment intersects

with our body so we want to keep that that health intact or else that

leakiness like i kind of showed in that picture earlier was going to wreak havoc in our bodies so

what are the five r’s in functional medicine

here is the 5r approach so we want to

remove what do we want to remove we want to remove

stressors what are those stressors it’s not necessarily going to be things like mental emotional

physical stressors that will kind of play into this as well we want to think about stressors that negatively affect

the environment of our gastrointestinal tract and these could be

food sensitivities or allergies and this is why like why we recommend

quite a few of our patients to go through an elimination diet that will get rid of the most

inflammatory foods that are likely for keeping that cycle of leaky gut going and by removing those foods the gut has

time to heal by decreasing that overall inflammatory load while the foods themselves may not

be the reason a leaky gut it’s definitely not doing us any favors the immune system is always reacting to

these foods now the immune system can see because of that gut leakiness

also part of those food sensitivities are going to be part of those the pretty ubiquitous in the standard american diet

so that’s where gluten-free actually may help a lot of people it’s going to decrease inflammation in the body but

also corn dairy soy peanuts processed sugars egg

this all may cause an issue so well something about bacteria think about parasites think about yeast

so at some point or other in your journey at maxwell clinic you have done or you’re likely to do a

stool test it’s probably one of the favorite things that our patients do

not really i have some that ask me not to do it again so it gives us so much important

information though about how to best help you how i mentioned probiotics earlier

these stool tests will tell us kind of what your gut needs and by the amount of bacteria we see this beneficial

probiotics were able actually to recommend the right probiotic for you to

aid in building your health if you have bad bacteria in your gut

that’s going to continue that inflammatory issue and that gut leakiness so we’ll

have to use some kind of protocol using herbals or maybe even depending on your symptoms and antibiotic

aeroscience parasites they do happen um not everybody has them but the

stool test that we recommend gets three stool samples those parasites are sneaky and they like

to hide and by doing three samples we can usually catch that and they are really difficult to get rid

of but they do help to get rid of them for your health

yeast yeast overgrowth we have yeast that inhabit our guts um not normally

but if we have that imbalance of bacteria in our gut that can lead to a yeast overgrowth and

that’s why many people after you take an antibiotic you might women especially might get a yeast

infection yes also can kind of show up on your skin

and show up kind of in your mouth and on your tongue and show up kind of uh

and under skin folds and in kind of your your private areas so that could also signal a yeast

overgrowth in your intestines so again we might use uh some antifungals nectar antifungals or

anti-yeast medications and dietary interventions to help

balance that yeast our hope though with removing foods is

not to have you have to remove them forever though you may notice that you feel best if you have

if you continue to remove gluten or dairy from your diet or whatever you find that you react to after an elimination

diet we want to replace um what do we want to replace well we want

to replace those digestive secretions and what are those digestive secretions

well just like in the name you think of them as your digestive enzymes

digestive really begins in your mouth you have this mechanical digestion with this fun word called mastication this is

where you’ll start to get some of that chemical breakdown with cyber salivary kind of amylase to

start breaking that food down as you kind of go into the stomach you’re going to have

gastric acid that we want to replace hydro hydrochloric acid some issues with um

heartburn and reflux actually are because of low stomach acid and not too much stomach acid so

when you have those symptoms and you get prescribed something like nexium or or

pepcid or actually reducing acid more may actually continue to cause issues

we may need to replace hydrochloric acid we may need to replace

things like amylase lipase protease i come from your pancreas and help to break down proteins

fats and carbs

you also want to think about replacing bile acids if you don’t have a gallbladder you might have trouble digesting fats

you have insufficient action from your gallbladder you may have trouble digesting fats if you

notice that your stool is really greasy and you have to wipe a lot well you might have trouble digesting fats

so using uh enzymes like ox file can help kind of replace that

and help improve that if we’re not digesting uh our foods well

um then you won’t be able to again get the all the goodness from our foods when you go

through all that trouble to change your diet and eat better so medications aging

are also going to change kind of how much of those enzymes we secrete our ability to do so

the third are re-inoculate

what do we re-inoculate well we want to re-inoculate prebiotics and

we want to re-inoculate with probiotics probiotics are a good bacteria

when we have enough of those good bacteria the beneficial ones mostly

being our favorites are lactobacillus and bifidobacterium

they help to keep the ph and the gut low they help to ward off or kill off any bad bacteria from overgrowing so if

you’ve insufficient amounts of that that can cause that dysbiosis to imbalance bacteria in your gut

so you are going to find probiotics and supplements as well as foods so

we want to help i always want to encourage nutrition overtaking things if we can

but sometimes to make a big intervention we need those consecrated concentrated doses of probiotics or of certain

minerals and nutrients in order to help get you better faster so

but fermented foods think about sour corn sauerkraut kimchi

yogurt miso tempe can be very beneficial for probiotic

health so prebiotics prebiotics i want you think about prebiotics to be like the food for

your probiotics they help to stimulate the growth of those beneficial bacteria

they if you’re taking a probiotic those prebiotics condense those probiotics that you’re taking to stay and move into

your gut so prebiotics are going to be coming

from fiber that fiber is going to be called inulin you’re going to get that from artichokes

from garlic beaks onion chicory tofu

and other soy products don’t recommend soy products if you have a sensitivity with soy though

also going to be in grains again are you sensitive to any type of grains and make sure they’re gluten free

but barley flax and oats um wheat not gluten free

but it’s a good prebiotic inulin source

when we what happens when we have that right balance again it

helps to keep the ph and the gut low um keeps bacteria from overgrowing protects you from any if you have to get

antibiotic antibiotic side effects

want to repair your gut as well how do we do that

so we’re going to repair we’re going to repair that gi lining we want to help tighten

those epithelial cells from being so leaky

how we do that we’re going to use antioxidants we’re going to use fish oil

we’re going to use zinc those antioxidants we’re going to use

are like vitamin c vitamin a vitamin e fiber so fiber

fiber is going to be food for those probiotics probiotics love fiber

they chomp down on that fiber and when they do they start to make these short chain fatty acids which help

to repair that gut lining as well

glutamine l-glutamine is an amino acid that helps to heal and seal the gut so again we’re trying to bring those cells

back to their healthy status something i want to mention too is

using 5-htp so

5-htp i wish i had that picture of the those

that cells again but if you notice on the in those gut cells on the tips of them they have these microvilli these little

finger-like projections that help to increase the surface area so what happens when that we have that

leaky gut depending on balance about it is and those microvilli can get worn down

and what we lose most microglia get worn down is something called dao diamine oxidase and that helps us to to deal

with histamines in the body and break them down um and so if you lack that dao you may have a lot of allergic type symptoms

so if those are denuded you have to try to grow those again to

help get your gut health back together and one thing that helps with that besides just supplementing with that dao

enzyme or cme is going to be 5 htp so 5 htp

aside from being a precursor to the neurotransmitters um

serotonin and melatonin in the body that help to support your mood and sleep they’re also

going to help grow those intestinal microphili i think that’s really uh fascinating

also because your gut actually is responsible for about 70 of those neurotransmitters

so if you’re having problems with like depression anxiety um i hope you are starting to see that

link of why that gut health matters

and then the last star is rebalance i know

i hope you don’t think you’re going to get away without some lifestyle recommendations so

we bounce what if we want to rebalance we want to make sure we have enough sleep and inadequate sleep can affect

our gi tract we want to exercise

kind of no we don’t want to exercise too little we don’t want to exercise too much too much exercise can be a stressor

on our bodies and can perpetuate inflammation so we have to kind of figure out what is right for you

also need to manage stress well dr woods did a really good um group visit

a couple weeks ago on breathing and it’s one of

the more difficult recommendations that we prescribe for people to follow i don’t it’s it

takes a lot of discipline but it can have the biggest impact because what we are trying to do is send a signal to

your brain to to relax if you have that fight or flight mechanism always on

the the body is not prioritizing healing it’s protect this prioritizing survival so you’re not going to be in thriving

mode you’re going to be in survival mode so it’s going to further impair digestion

so even if you’re like man i’m eating really well but i still feel like crap but if you’re over exercising you’re not

prioritizing sleep you’re not taking moments to relax then

that’s your problem so

those are our five r’s so i’d like to know

if you have any questions i’m gonna try to go ahead and

answer one for you so a lot of questions a question i get all the time is you know how long does

gut healing take and that depends we practice personalized

systems medicine and how long this takes kind of depends on where you’re at because

a lot of times you’re not going to get into the state of unhealth overnight

so that can almost take about as much time as a chit key to get unwell but i would have set an expectation for

somewhere i would say i mean try to look at least six months to a year

uh and that again is going to vary from person to person depending on your history and your needs

beyond what your environment’s like and what medications you’re already on

so i will see people that are relatively young and healthy and not a lot of issues i see them get

better they do an elimination diet we replenish omega-3 fatty acids iron vitamin d

and after like a couple months amazing they’re they’re feeling great others

there’s a lot more time so but um some patients may see benefit in

three months some six i’m a year but again depends on all the issues that are kind of found

so

well i do hope this has been really helpful um

about our approach to gut healing and

hopefully why i hope you understand why we’ve recommended some of the things we do in order to get you well so even though i

listed those five r’s in a particular order those some of those mechanisms are going to happen all

at once um or maybe they’ll be gradually layered on we always want to tailor what we do to

you i never want anyone to feel overwhelmed with what we’re doing

but also how much we’re able to do at a time may give us more robust results and

healing so the expectation needs to be depending on what we’re doing it might

just take more time

i appreciate that expression of thankfulness

any other questions i would love to help you understand

anything about this topic more so

i’ll leave this just for maybe another minute i really appreciate you spending

friday afternoon with me

you would like to explore any of these options i encourage you to reach out to your

maxwell clinician we are very passionate about this topic

so i would say if you find yourself not getting better and it’s been a while since we’ve looked at your gut

i i would ex i would have recommended reassessments

i think after the first of the year is a great time to reset an elimination diet

this is what you notice that you might have forgotten

i also want to you to pay attention to this is a really awkward question that i

ask patients that that matters so

what’s your school like you ask everybody if you have a bowel movement daily and

growing up i never paid attention to it and i realized as i get older it’s how important it is

and and kind of the traditional teaching is that you just go as much as you need to

go so regular for some was believed to be if you go every three days and you go every three days

but honestly if you’re eating food you should be eliminating daily

so ideally if you look at a bristol school chart it has a

a gradient of what school should look like so the basics though as you know is your

stool is it looking like pebbles is it looking like logs is it looking like a snake is it looking like pudding

or is it looking like tea the ideal stool is going to look like a snake

if you’re looking kind of more like logs you might need more hydration or more fiber

you have pebbles that’s more constipation may need some magnesium citrate uh fiber water maybe probiotic if you’re

having loose stool pudding tea again we think about

maybe you need digestive enzymes or vital acids your gut has your entire nervous system

and so if you are kind of an anxious and nervous person then

kind of again not taking that time to de-stress that’s going to regulate that sympathetic that fight or flight you’re

going to have quicker evacuation of your stool so your body does not prioritize

breaking down foods into their nutrients and micronutrients and

and it’s just fast and accumulation so that could be an infection as well so

there’s so much we can learn about our poop so

even if you don’t have any digestive symptoms issues could still be coming from your

and there’s much we can do and look into to help improve that so

well once again i appreciate your time and i hope this has been very informative

and hopefully interesting have a great weekend

Restoring the Gut: Understanding the 5 Rs to Healing Leaky Gut (2024)
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